[EDIT: In case it's not obvious, I've written the title to get the attention of the Affymetrix, as I don't think they've read the contents of my blog posts, despite their picking me as a poster boy for their propaganda - not because I think they actually suck...]
It has come to my attention that the people at Affymetrix have taken to using a screen shot of my blog to argue that bloggers have prematurely called for the death of microarrays – and their proof to the contrary is that they’re still around.
Affymetrix, you may have noticed that my title for this blog is strongly worded – and that’s because I don’t think you’ve bothered to read the actual posts. In fact, there are two of them:
My entire argument revolves around the fact that sequencing is getting cheaper – and thus, the concept of doing targeted sequencing via a platform for which sequencing costs are NOT getting cheaper is a ridiculous concept in the long run. Furthermore, I didn’t say that arrays should disappear entirely, but rather that they should just be dropped for cutting edge research.
There are a few exceptions for areas where you willfully want to blind yourself: Diagnostics is probably the most prominent, and is likely a growing sector in to which Affymetrix will be able to expand and grow.
Thus, Affymetrix, your continued existence is not a counter-argument.
In fact, your continued success is also not a counter argument.
There will always be a place for microarrays, but that place is not going to be cutting edge research. Really, how long do you think exon capture experiments are going to last, when the cost of 30X WGS hits $500?
Seriously, Affymetrix, if you’re going to ridicule me for my opinions, take the time to read what my opinions are.
And, by the way, Affymetrix, have you seen this picture? (Thanks Daniel!)
By the way, if anyone knows the cost per base of sequencing for an Affymetrix chip, obtaining the same dynamic range and error profile as an Illumina platform run, I would love to know that number.